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Opposing Actions of Dehydroepiandrosterone and Corticosterone in Rats

✍ Scribed by M. McIntosh; H. Bao; C. Lee

Book ID
114436261
Publisher
Royal Society of Medicine Press
Year
1999
Tongue
English
Weight
592 KB
Volume
221
Category
Article
ISSN
0037-9727

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✍ Ling-Ling Chang; Wan-Song Alfred Wun; Paulus S. Wang πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 199 KB

## Abstract We have demonstrated that dehydroepiandrosterone (DHEA) acts directly on rat zona fasciculata‐reticularis (ZFR) cells to diminish corticosterone secretion by an inhibition of post‐cAMP pathway, and decreases functions of steroidogenic enzymes after P450~scc~ as well as steroidogenic acu