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Opioid rotation in cancer pain

โœ Scribed by Sebastiano Mercadante

Book ID
107550067
Publisher
Springer
Year
1998
Tongue
English
Weight
77 KB
Volume
2
Category
Article
ISSN
1534-3081

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๐Ÿ“œ SIMILAR VOLUMES

Opioid rotation in patients with cancer
Opioid rotation in patients with cancer pain: A retrospective comparison of dose ratios between methadone, hydromorphone, and morphine
โœ Eduardo Bruera; Jose Pereira; Sharon Watanabe; Michelle Belzile; Norma Kuehn; Jo ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 531 KB

## BACKGROUND. When a change of opioid is considered, equianalgesic dose tables are used. These tables generally propose a dose ratio of 5:l between morphine and hydromorphone. In the case of a change from subcutaneous hydromorphone to methadone, dose ratios ranging from 1:6 to 1:10 are proposed.

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BACKGROUND. Some patients with cancer pain may develop uncontrolled adverse effects, including generalized myoclonus, delirium, nausea and emesis, or severe sedation before achieving adequate analgesia during opioid dose titration. Sequential therapeutic trials should be considered to determine the