Opioid peptide receptor studies. 12. Bup
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Dana V. Romero; John S. Partilla; Qaio-Xi Zheng; Simone O. Heyliger; Qing Ni; Ke
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Article
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1999
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John Wiley and Sons
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English
⚖ 511 KB
We utilized the [ 35 S]-GTP-␥-S functional binding assay to determine the selectivity of opioid receptor agonists in guinea pig caudate membranes. The study focused on two opioid agonists used for treating opioid-dependent patients: methadone and buprenorphine. Selective antagonists were used to gen