Opiate-induced motor stimulation is regulated by γ-aminobutyric acid type B receptors found in the ventral tegmental area in mice

Chronic nicotine and smoke treatment mod

Chronic nicotine and smoke treatment modulate dopaminergic activities in ventral tegmental area and nucleus accumbens and the γ-aminobutyric acid type B receptor expression of the rat prefrontal cortex

✍ Shu-Peng Li; Moon Seok Park; Jong Hun Kim; Myeong Ok Kim 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 516 KB

Dopaminergic afferents from the mesencephalic areas, such as ventral tegmental area (VTA), synapse with the ␥-aminobutyric acid (GABA)-ergic interneurons in the prefrontal cortex (PFC). Pharmacological and electrophysiological data show that the reinforcement, the dependenceproducing properties, as