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Ophthalmoplegic and lower cranial nerve variants merge into each other and into classical Guillain-Barré syndrome

✍ Scribed by J.P. ter Bruggen; F.G.A. van der Meché; A.E.J. de Jager; C.H. Polman


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
97 KB
Volume
21
Category
Article
ISSN
0148-639X

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✦ Synopsis


We delineated the place of cranial nerve variants within the concept of clinically defined Guillain-Barre ´syndrome (GBS). In the ophthalmoplegic variant (n = 7) the oculomotor nerves were early involved. In a lower cranial nerve variant (n = 9) the cranial nerves IX, X, and XI were early involved. During progression considerable overlap occurred between these two variants, but also with the classically ascending variant of clinically defined GBS. These findings indicate common immune mechanisms in all GBS variants.