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Openers of calcium-activated potassium channels and endothelium-dependent hyperpolarizations in the guinea pig carotid artery

✍ Scribed by V. Leuranguer; P. Gluais; P. M. Vanhoutte; T. J. Verbeuren; M. Félétou


Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
240 KB
Volume
377
Category
Article
ISSN
0028-1298

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The potential of the potassium channel activator cromakalim and its active enantiomer BRL 38227 as inhaled bronchodilators has been evaluated in the guinea-pig, in comparison with nifedipine, salbutamol and aminophylline. Inhaled cromakalim and BRL 38227 prolonged the time before histamine-induced c