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Open study evaluating lamotrigine efficacy and safety in add-on treatment and consecutive monotherapy in patients with carbamazepine- or valproate-resistant epilepsy

✍ Scribed by Sergiusz Jozwiak; Artur Terczynski


Book ID
117832336
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
188 KB
Volume
9
Category
Article
ISSN
1059-1311

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Thirteen drug-resistant epilepsy patients received loreclezole as add-on therapy. The trial lasted 6 months. Loreclezole was dosed to reach a target plasma concentration between 1 and 3 mg/l. The seizure frequency in the total group decreased by 23%. A reduction of 50% or more was observed in four p