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OP18/stathmin binds near the C-terminus of tubulin and facilitates GTP binding

✍ Scribed by Francisco José Moreno; Michel Bagnat; Filip Lim; Jesús Avila

Book ID
114429887
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
435 KB
Volume
262
Category
Article
ISSN
1432-1327

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## Abstract Previous deletion studies have suggested that Tyr306 has an important influence on the properties of protein phosphatase‐1 (PP1). To test this inference, we constructed three site‐directed mutants, PP1Y306A, PP1Y306K, and PP1Y306E. The specific activity of PP1Y306A was 3.5‐fold higher t