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Ontogeny of the cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver, lung, and thymus

โœ Scribed by Thomas A. Gasiewicz; William C. Ness; George Rucci


Book ID
115757779
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
484 KB
Volume
118
Category
Article
ISSN
0006-291X

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Aryl hydrocarbon hydroxylase (AHH, cytochrome P1-450) is induced in chick liver very early during embryonic development if embryos are treated with 3-methylcholanthrenetype compounds such as 3,4,3'4'-tetrachlorobiphenyl. In mammals, AHH induction is known to be mediated by the Ah receptor. Liver fro