The biochemical characteristics and the distribution of pituitary adenylate cyclaseactivating polypeptide (PACAP) binding sites have been investigated in the brain of the frog Rana ridibunda by using [ 125 I]PACAP27 as a radioligand. Membrane-binding studies revealed the existence of high-affinity r
โฆ LIBER โฆ
Ontogeny of pituitary adenylate cyclase-activating polypeptide (PACAP) in the frog (Rana ridibunda) tadpole brain: Immunohistochemical localization and biochemical characterization
โ Scribed by Maura Mathieu; Laurent Yon; Ismail Charifou; Michele Trabucchi; Mauro Vallarino; Claudia Pinelli; Alain Fournier; Rakesh K. Rastogi; Hubert Vaudry
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 865 KB
- Volume
- 431
- Category
- Article
- ISSN
- 0021-9967
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The structure of the neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) has been characterized in several species including protochordates, fish, amphibians, birds, and mammals. Although PACAP has been shown to stimulate frog pituitary and adrenal cell activity, the structure of