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Ontogeny of cortisol-cortisone interconversion in human tissues: A role for cortisone in human fetal development

✍ Scribed by Beverley E. Pearson Murphy

Book ID: 116002351
Publisher: Elsevier Science
Year: 1981
Tongue: English
Weight: 853 KB
Volume: 14
Category: Article
ISSN: 0022-4731
DOI: 10.1016/0022-4731(81)90226-0

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## Abstract The measurement of the urinary free cortisol–cortisone ratio has been reported to be a sensitive indicator of renal 11 __β__‐hydroxysteroid dehydrogenase type 2 (11 __β__‐HSD 2) activity. This converts biologically active cortisol to inactive cortisone. A decrease in its activity (e.g.