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Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat

✍ Scribed by Derek L. Choi-Lundberg; Martha C. Bohn


Book ID
115546406
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
842 KB
Volume
85
Category
Article
ISSN
0165-3806

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Glial cell line-derived neurotrophic factor (GDNF) was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is a more potent survival factor for dopaminergic neurons and the noradrenerg