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Ontogenic development of the TTX-sensitive and TTX-insensitive Na+ channels in neurons of the rat dorsal root ganglia

โœ Scribed by Nobukuni Ogata; Hideharu Tatebayashi


Book ID
119101931
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
865 KB
Volume
65
Category
Article
ISSN
0165-3806

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Slow inactivation of tetrodotoxin-insens
โœ Nobukuni Ogata; Hideharu Tatebayashi ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 884 KB

Whole-cell patch-clamp experiments were performed with neurons cultured from rat dorsal root ganglia (DRG). Two types of Na+ currents were identified on the basis of sensitivity to tetrodotoxin. One type was blocked by 0.1 nM tetrodotoxin, while the other type was insensitive to 10 microM tetrodotox