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Onset of zygotic transcription and maternal transcript legacy in the rabbit embryo

✍ Scribed by A. Brunet-Simon; G. Henrion; J.P. Renard; V. Duranthon


Book ID
111659705
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
156 KB
Volume
58
Category
Article
ISSN
1040-452X

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In most species, transcription is essentially silent during the first mitotic cell cycles that follow fertilization. This means that the regulation of gene expression in early embryos heavily relies on the translational activation or inactivation of maternal mRNAs. In mammals, the mechanisms that co