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Onset of androgen action in MCF-7 human breast cancer cells is not accompanied by receptor depletion

✍ Scribed by Ellen Shapiro; Marc E. Lippman


Book ID
116005077
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
663 KB
Volume
22
Category
Article
ISSN
0022-4731

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Lactogenic hormones which bind to the PRLR are likely to be growth-stimulatory in human breast-cancer cells. Oestrogen and progesterone control cellular expression of the PRLR however, elevated androgen levels in some breast-cancer patients raised the possibility that androgens may also influence br