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Onset and duration of action of benzodiazepines as determined by inhibition of (3H)-flunitrazepam binding

✍ Scribed by Dr. Vimala H. Sethy; Jonathan W. Francis; Grey Elfring

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
291 KB
Volume
10
Category
Article
ISSN
0272-4391

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Monensin inhibits the binding of 3H-flun
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Effects of monensin were examined on the intracellular processing of the GABAA/benzodiazepine receptor (GABAA/BZDR) in neuron cultures derived from embryonic chicken brain, using 3H-flunitrazepam as the probe for the benzodiazepine modulator site on the receptor. Incubation of cultures with 0.1 or 1