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One-Step, Three-Component Synthesis of Pyridines and 1,4-Dihydropyridines with Manifold Medicinal Utility †

✍ Scribed by Evdokimov, Nikolai M.; Magedov, Igor V.; Kireev, Artem S.; Kornienko, Alexander

Book ID
119979215
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
84 KB
Volume
8
Category
Article
ISSN
1523-7060

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An efficient one-step synthesis of 1,4-d
An efficient one-step synthesis of 1,4-dihydropyridines via a triphenylphosphine-catalyzed three-component Hantzsch reaction under mild conditions
✍ Abdelmadjid Debache; Wassima Ghalem; Raouf Boulcina; Ali Belfaitah; Salah Rhouat 📂 Article 📅 2009 🏛 Elsevier Science 🌐 French ⚖ 293 KB

a b s t r a c t An efficient one-step synthesis of 1,4-dihydropyridines in good to excellent yields via the triphenylphosphine-catalyzed Hantzsch three-component reaction of an aromatic aldehyde, ethyl acetoacetate and ammonium acetate is described.