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One-Step Synthesis of Tröger's Base Hybrids Containing at Least One Halogen Atom

✍ Scribed by Masoud Faroughi; Kai-Xian Zhu; Paul Jensen; Donald C. Craig; Andrew C. Try


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
179 KB
Volume
2009
Category
Article
ISSN
1434-193X

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## Abstract The yields of 2,8‐dihalo analogues of Tröger's base in the condensation between 4‐haloanilines and paraformaldehyde was found to be highly sensitive to the crucial reaction parameters of scale, stoichiometry and temperature. The reaction conditions were optimized allowing for the semi‐l