One-Step Synthesis of 3-Aryl- and 3,4-Diaryl-(1H)-pyrroles Using Tosylmethyl Isocyanide (TOSMIC).
✍ Scribed by Nicholas D. Smith; Dehua Huang; Nicholas D. P. Cosford
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 129 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A mild and convenient method for the synthesis of 4(3)‐substituted 3(4)‐nitro‐1__H__‐pyrroles and 3‐substituted 4‐methyl‐2‐tosyl‐1__H__‐pyrroles from nitroolefins and tosylmethyl isocyanide (TosMIC) in ionic liquid 1‐butyl‐3‐methylimidazolium bromide ([bmIm]Br) was developed. The react
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