One-step synthesis of 1,4-benzodioxanes by reaction of 1,2-cyclohexanedione with vicinal diols promoted by dichlorobis(benzonitrile)palladium(II)
✍ Scribed by Mincione, Enrico; Sirna, Antonio; Covini, Daniele
- Book ID
- 121419440
- Publisher
- American Chemical Society
- Year
- 1981
- Tongue
- English
- Weight
- 267 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
## Abstract The reactive 1 : 1 adducts in the reaction between Ph~3~P and dialkyl acetylenedicarboxylates have been trapped with ‘tosylmethyl isocyanide’ (TsMIC; **1**) to yield dialkyl 2‐[(4‐methylphenyl)sulfonyl]‐1__H__‐pyrrole‐3,4‐dicarboxylates **3** (__Scheme 1__). The structures of the highly
N-t-Butylacetamidines 1 on heating with methyl vinyl ketone, acrolein or crotonaldehyde gave the 2,3-dihydropyridine derivatives 4, 5 or 6 via N-alkylation of the acetamidines 1. Reaction of amidines 1 with phenyl 1-propenyl ketone, benzalacetone or chalcone gave 3,4-dihydropyridine derivatives 8, 9