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One-step preparation of 3-alkoxypyrazine-2-carbonitriles from pyrazine-2,3-dicarbonitriles and related reactions

โœ Scribed by Takakazu Kojima; Fumihiko Nagasaki; Yozo Ohtsuka

Book ID
112125977
Publisher
Journal of Heterocyclic Chemistry
Year
1980
Tongue
English
Weight
329 KB
Volume
17
Category
Article
ISSN
0022-152X

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Synthesis of pteridine derivatives relat
Synthesis of pteridine derivatives related to folic acid and methanopterin from pyrazine-2,3-dicarbonitrile
โœ Masaru Tada; Yasuhiro Asawa; Mamoru Igarashi ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 691 KB

## Abstract Pteridine derivatives related to folic acid and methanopterin were synthesized by two methods. The first synthesis is initiated by the radical substitution of 5โ€methylpyrazineโ€2,3โ€dicarbonitrile (3) with the (__N__โ€acylanilino)alkyl radical to give 6โ€methylโ€5โ€(__N__โ€acylanilino)alkylpyr