One-pot synthesis of β-hydroxysulfides from styrenes and disulfides using the Zn/AlCl3 system

✍ Scribed by Barahman Movassagh; Mozhgan Navidi

• Publisher: Elsevier Science
• Year: 2008
• Tongue: French
• Weight: 161 KB
• Volume: 49
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2008.09.071

✦ Synopsis

A simple, general, and highly regioselective procedure has been developed for the one-pot synthesis of b-hydroxysulfides in good yields from various styrenes and disulfides by cleavage of the S-S bond with a Zn/AlCl 3 system in aqueous acetonitrile at 80 °C and in the presence of oxygen.