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One-pot synthesis of the indole derivative 4-chloro-3-sulphamoyl-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)benzamide (indapamide)

✍ Scribed by Barbara Ziobro; Barbara Sienkiewicz; Piotr Kowalski

Publisher: Journal of Heterocyclic Chemistry
Year: 2004
Tongue: English
Weight: 110 KB
Volume: 41
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570410115

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✦ Synopsis

Abstract

New methods for the synthesis the indole derivative, Indapamide (1), using mixed anhydrides of the general formula R1COOCOOR2 (2) or DCC (N,N'‐dicyclohexylcarbodiimide) (3), are described.

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