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One-pot synthesis of pyridine derivatives via diels-alder reactions of 2,4-dimethyl-5-methoxyoxazole

✍ Scribed by Samir Bondock

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
155 KB
Volume
16
Category
Article
ISSN
1042-7163

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✦ Synopsis

Abstract

A novel series of pyridine derivatives with anticipated biological activity have been synthesized via Diels‐Alder reactions of 2,4‐dimethyl‐5‐methoxyoxazole with different types of dienophiles. The regioselectivity of the cycloaddition was inverted from methylacrylate to tert‐butylacrylate. The structural elucidation of the new compounds was carried on the basis of spectral and X‐ray analyses. © 2005 Wiley Periodicals, Inc. Heteroatom Chem 16:49–55, 2005; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20064

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