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One-pot synthesis of protected homoallyl amines

✍ Scribed by Siem J. Veenstra; Priska Schmid


Book ID
104256203
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
249 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis


An efficient one-pot procedure for the synthesis of protected homoallyl amines from aldehydes or aldehyde acetals, carbamates and allyltrimethylsilane under influence of borontrifluoride etherate was developed. Scope and limitations of the aldehyde and carbamate components are reported.


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ChemInform Abstract: One-Pot Synthesis o
✍ S. J. VEENSTRA; P. SCHMID πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 33 KB πŸ‘ 2 views

One-Pot Synthesis of Protected Homoallyl Amines. -Scope and limitations of an efficient one-pot procedure for the synthesis of the title amines such as (IV), (VI), and (IX) are presented. An alternative to BF3β€’OEt2 is SnCl4 at -10 β€’ C whereas TiCl4 or TFA lead to decomposition. -(VEENSTRA, S.