One-Pot Synthesis of Protected Homoallyl Amines. -Scope and limitations of an efficient one-pot procedure for the synthesis of the title amines such as (IV), (VI), and (IX) are presented. An alternative to BF3β’OEt2 is SnCl4 at -10 β’ C whereas TiCl4 or TFA lead to decomposition. -(VEENSTRA, S.
β¦ LIBER β¦
One-pot synthesis of protected homoallyl amines
β Scribed by Siem J. Veenstra; Priska Schmid
- Book ID
- 104256203
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 249 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
An efficient one-pot procedure for the synthesis of protected homoallyl amines from aldehydes or aldehyde acetals, carbamates and allyltrimethylsilane under influence of borontrifluoride etherate was developed. Scope and limitations of the aldehyde and carbamate components are reported.
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