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One-pot synthesis of novel 2′-deoxyuridine derivatives containing α-aminophosphonate moieties

✍ Scribed by Zhi-Qiang Shang; Ru-Yu Chen; You Huang

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
156 KB
Volume
18
Category
Article
ISSN
1042-7163

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✦ Synopsis

Abstract

A series of α‐aminophosphonate derivatives of 2′‐deoxyuridine (8a–k) have been prepared from 5′‐O‐tert‐butyldimethylsilyl‐3′‐amino‐2′, 3′‐dideoxyuridine in good yields. The structures of all the products were confirmed by ^1^H NMR, ^31^P NMR, ^31^C NMR, and IR spectroscopy, and mass spectrometry and elemental analyses. © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:230–235, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20288

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