One-pot Synthesis of N-Hydroxylacridine Derivatives in Water

✍ Scribed by Da-Qing Shi; Jie Mou; Qi-Ya Zhuang; Xiang-Shan Wang

• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 70 KB
• Volume: 23
• Category: Article
• ISSN: 0256-7660
• DOI: 10.1002/cjoc.200591223

✦ Synopsis

Abstract

N‐Hydroxylacridinedione derivatives were synthesized by three‐component reaction of aromatic aldehydes, 1,3‐dicarbonyl compounds and hydroxylamine hydrochloride using triethylbenzylammonium chloride (TEBA) as the catalysis in water. The reaction has many advantages including good yields, easy to be separated and environmental friendliness.