One-Pot synthesis of isothiachromene, isochromene, isoquinoline and tetrahydronaphthalene derivatives
β Scribed by A. M. El-Sayed; H. Abdel-Ghany
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2000
- Tongue
- English
- Weight
- 463 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0022-152X
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β¦ Synopsis
Abstract
A new series of tetrahydronaphthalene, isothiachromene, isochromene and isoquinoline derivatives were synthesized by reacting cyclohexylidenemalononitrile with active nitriles, active halo compounds, carbon disulfide, aldehydes, isothiocyanates and isocyanates, respectively.
π SIMILAR VOLUMES
Synthesis of 4-thioureidobenzoic acid (2), which on cyclization with ethyl chloroacetate gave 4-(2-imino-5-oxothiazolidin-3-yl)-benzoic acid (3), which on further reacting with benzoin (4) in the presence of polyphosphoric acid afforded the synthesis of 2-imino-3-(-1-oxo-3,4-diphenyl-1H-isochromen-6
## Abstract Novel thiazolylisochromene derivative (VII) is synthesized by reaction of benzoic acid (V) with benzoin, and transformed into corresponding isoquinoline derivatives (IX).
A new and facile method for the preparation of isoquinolinequinone derivatives has been developed. Treatment of 2-acyl-1,4-naphthoquinones or 2-acyl-5,6-dimethyl-1,4-benzoquinones with enamines (or imines), followed by addition of aqueous NH 3 in MeOH afforded benz[g]isoquinoline-5,10-dione or isoqu
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract A fourβcomponent reaction for the synthesis of 1,2βdihydroisoquinoline derivatives is described. The __Huisgen__ 1,4βdipolar intermediate, which is produced from isoquinoline and an electronβdeficient acetylene compound **1**, reacts with H~2~O in the presence of diketene to produce 1,2