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One-Pot Synthesis of Bicyclic β-Alkoxy Amides from Cyanohydrin Ethers

✍ Scribed by Xiao, Qing; Floreancig, Paul E.


Book ID
126110673
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
107 KB
Volume
10
Category
Article
ISSN
1523-7060

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A/~tract:. A new, one pot synthesis of bicyclic ethers starting from ct, l~-unsaturated ketones containing an additional isolated olefinic bond is proposed. It relies on highly chemoselective hydrogenation of the enone group to the corresponding alcohol in the presence of supported copper catalysts,