One-pot synthesis of angular furocoumarins: A simple protocol involving unprecedented intramolecular aldol condensation

✍ Scribed by Lakshmi Narayan Dutta; Banani De; Amarendra Patra

• Publisher: Journal of Heterocyclic Chemistry
• Year: 2008
• Tongue: English
• Weight: 247 KB
• Volume: 45
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.5570450306

✦ Synopsis

Abstract

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Refluxing of hydroxycoumarinyl ketones with methyl γ‐bromocrotonate in dry acetone in presence of anhydrous K~2~CO~3~ afforded substituted angelicins (angular furanocoumarins) in satisfactory yields through intramolecular Aldol condensation followed by β‐elimination.