𝔖 Bobbio Scriptorium
✦   LIBER   ✦

One-pot synthesis of 2-trifluoromethylchromones

✍ Scribed by Isabel C. Henao Castañeda; Sonia E. Ulic; Carlos O. Della Védova; Nils Metzler-Nolte; Jorge L. Jios

Book ID
104098834
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
256 KB
Volume
52
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

a b s t r a c t

We report a simple and suitable method for the preparation of useful 2-trifluoromethylchromones in one step, in high yields and avoiding the use of solvents. We were able to detect the intermediate of this reaction. Furthermore a mechanism for the formation of the 7-methoxy-3-trifluoroacetyl-2-trifluoromethylchromone through the unexpected double trifluoroacetylation of 4-methoxy-2hydroxyacetophenone followed by dehydration is also proposed. All compounds are fully identified and characterized by spectroscopic techniques.

📜 SIMILAR VOLUMES

ChemInform Abstract: One-Pot Synthesis o
ChemInform Abstract: One-Pot Synthesis of 2-Trifluoromethylchromones.
✍ Isabel C. Henao Castaneda; Sonia E. Ulic; Carlos O. Della Vedova; Nils Metzler-N 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views

## Abstract A simple procedure is presented for the reaction of 2‐hydroxyacetophenones (I) with trifluoroacetic anhydride.

One-Pot Synthesis of 2-Deoxysugars
One-Pot Synthesis of 2-Deoxysugars
✍ V. I. Kornilov; Z. I. Glebova; T. P. Sudareva 📂 Article 📅 2005 🏛 Springer 🌐 English ⚖ 26 KB