One-pot synthesis of 2-aminobenzimidazoles using 2-chloro-1,3-dimethylimidazolinium chloride (DMC)
โ Scribed by Gerald D. Artman III; Catherine F. Solovay; Christopher M. Adams; Brian Diaz; Martin Dimitroff; Takeru Ehara; Danlin Gu; Fupeng Ma; Donglei Liu; Bridget R. Miller; Teresa E. Pick; Daniel J. Poon; David Ryckman; David A. Siesel; Brady S. Stillwell; Tyson Swiftney; Jonathan P. van Dyck; Chun Zhang; Nan Ji
- Book ID
- 104098180
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 724 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
a b s t r a c t 2-Chloro-1,3-dimethylimidazolinium chloride (DMC or DMC-Cl) has been found to effectively and rapidly generate 2-aminobenzimidazoles from 1,2-diaminoarenes and isothiocyanates in moderate to good yields at room temperature in a one-pot operation.
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Various 1,6-anhydro sugars have been synthesized directly from the corresponding unprotected glycopyranoses in excellent yields by using 2-chloro-1,3-dimethylimidazolinium chloride (DMC) as a dehydrative condensing agent. The reactions took place smoothly under mild reaction conditions in aqueous me