In order to obtain diastereomeric control in the azole catalyzed coupling reaction of methylphosphonamidites, 2-(2",4",6"-trimethylbiphenyl-2-yl)-4,5-dicyanoimidazole 2 was synthesized. With its use as activator Rp-diastereoselective synthesis of dinucleoside methylphosphonates could be achieved for
✦ LIBER ✦
One pot RP-diastereoselective synthesis of dinucleoside methylphosphonates using methyldichlorophosphine
✍ Scribed by Thomas Löschner; Joachim Engels
- Book ID
- 104244888
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 229 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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