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One-Pot Efficient Synthesis of Fully Substituted 1,3,4-Oxadiazole Derivatives from (N-Isocyanimino)triphenylphosphorane, Carboxylic Acids, and Aromatic Bis-Aldehydes

✍ Scribed by Ramazani, Ali; Ahmadi, Yavar; Mahyari, Amir

Book ID: 115465957
Publisher: Taylor and Francis Group
Year: 2011
Tongue: English
Weight: 273 KB
Volume: 41
Category: Article
ISSN: 0039-7911
DOI: 10.1080/00397911.2010.501480

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## Abstract The 1 : 1 imine intermediate **7** generated by the addition of a primary amine **2** to chloroacetone (**1**) is trapped by (isocyanoimino)triphenylphosphorane (**4**) in the presence of an aromatic carboxylic acid **3** and leads to the formation of the corresponding iminophosphorane