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One-Flow, Multistep Synthesis of Nucleosides by Brønsted Acid-Catalyzed Glycosylation

✍ Scribed by Dr. Adam Sniady; Dr. Matthew W. Bedore; Prof. Dr. Timothy F. Jamison


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
408 KB
Volume
123
Category
Article
ISSN
0044-8249

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The zeolite H-Beta catalyzes the retro-Diels-Alder reaction of a range of cyclopentadiene cyclo-adducts at moderate temperatures and ambient pressure, in the presence of an active dienophile. The active catalyst was identified and optimum reaction conditions established after screening a range of ze