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One-electron oxidation of DNA: thymine versus guanine reactivity

✍ Scribed by Kanvah, Sriram; Schuster, Gary B.


Book ID
118223524
Publisher
Royal Society of Chemistry
Year
2010
Tongue
English
Weight
340 KB
Volume
8
Category
Article
ISSN
1477-0520

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The effects of methyl and bromo groups at C5 of C on the one-electron oxidation rate of G, and on the hole transfer rate in DNA have been investigated. The rates of one-electron oxidation of G and hole transfer from Py + to 8-oxo-7,8-dihydroguanine were suppressed and enhanced by introducing bromo a