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One Century of Aryne Chemistry

✍ Scribed by Hans Henning Wenk; Michael Winkler; Wolfram Sander


Book ID
101939586
Publisher
John Wiley and Sons
Year
2003
Weight
49 KB
Volume
34
Category
Article
ISSN
0931-7597

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Cover Picture: One Century of Aryne Chem
✍ Hans Henning Wenk; Michael Winkler; Wolfram Sander πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 44 KB πŸ‘ 3 views

**A century of aryne chemistry has not dampened the interest in this class of reactive intermediates. The cover picture shows the structure of a calicheamicin–DNA complex, the β€œwarhead” of which is a cyclic enediyne unit (highlighted). The biological activity of the enediyne cytostatics is based on