Cover Picture: One Century of Aryne Chem
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Hans Henning Wenk; Michael Winkler; Wolfram Sander
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Article
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2003
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John Wiley and Sons
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English
β 44 KB
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**A century of aryne chemistry has not dampened the interest in this class of reactive intermediates. The cover picture shows the structure of a calicheamicinβDNA complex, the βwarheadβ of which is a cyclic enediyne unit (highlighted). The biological activity of the enediyne cytostatics is based on