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Oncolytic Gene Therapy Combined with Double Suicide Genes for Human Bile Duct Cancer in Nude Mouse Models

โœ Scribed by Yoh Kojima; Kazuo Honda; Hirofumi Hamada; Nobuaki Kobayashi


Book ID
116705340
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
674 KB
Volume
157
Category
Article
ISSN
0022-4804

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## Abstract Cancer gene therapy and oncolytic virotherapy have been studied extensively. However, their clinical application is hampered by their weak anticancer activity. We previously constructed a replicating adenovirus (OBPโ€301, Telomelysin), in which the human telomerase reverse transcriptase