## Abstract ## Introduction Quality‐of‐life analysis is essential in determining the eventual outcome after treatment for head and neck cancer. This is particularly important when functional sequelae of treatment cause significant morbidity. The purpose of this study is to evaluate the functional
Oncologic and functional results after transhyoid surgical approach for cancer of the base of tongue
✍ Scribed by Juan P. Rodrigo; Juan Pablo Díaz-Molina; Carla Moreno; Carlos Suárez
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 159 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1043-3074
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Background
The optimal treatment for base of tongue cancer remains unclear, especially in advanced stages.
Methods
We retrospectively review 84 previously untreated patients that underwent a transhyoid resection of a base of tongue carcinoma. Sixty‐four patients (76%) underwent postoperative radiotherapy.
Results
Five patients had stage II disease, 6 had stage III, 58 had stage IVA, and 15 had stage IVB. The overall recurrence rate was 68%. Five‐year disease‐specific survival rates by stage were 100%, 67%, 27%, and 8% for stage II to IVB, respectively (p = .0007). Multivariate analysis showed that the presence of lymph node metastases was an independent predictor of reduced disease‐specific survival rates (p = .02). All patients maintained an intelligible voice, and oral alimentation was successfully recovered in 97.5% of them.
Conclusions
The transhyoid approach allowed adequate resection of base of tongue cancers with low morbidity and acceptable functional results, but the oncologic outcomes in advanced stages are poor. Head Neck, 2011
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