## Abstract The CC531 cell line has been widely used to study different aspects of tumor growth and metastasis and provides an excellent experimental platform to develop novel antitumor strategies. To characterize the CC531 model at the molecular level, we screened for mutations in genes covering i
✦ LIBER ✦
Oncogenic transformation by β-catenin: deletion analysis and characterization of selected target genes
✍ Scribed by Aoki, Masahiro; Sobek, Vera; Maslyar, Daniel J; Hecht, Andreas; Vogt, Peter K
- Book ID
- 110066953
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 233 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0950-9232
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Alterations in the rate of cellular tryptophan metabolism are involved in mediating important biological activities associated with cytokines and growth factors. Indoleamine 2,3-dioxygenase (IDO) and tryptophanyl-tRNA synthetase are enzymes of tryptophan metabolism whose expression in a variety of c