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Oncogenic signaling from the hematopoietic growth factor receptors c-Kit and Flt3

✍ Scribed by Kristina Masson; Lars Rönnstrand


Book ID
113528336
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
535 KB
Volume
21
Category
Article
ISSN
0898-6568

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Mutations within the Steel and Dominant Spotting loci of mice have led to the recent identification of a growth factorheceptor system required for the normal development of germ cells, pigment cells and hematopoietic cells. Interactions between the praducts of these genes, Steel factor and c-Kit res