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Oncogenic pathways in hereditary and sporadic breast cancer

✍ Scribed by P. Kenemans; R.A. Verstraeten; R.H.M. Verheijen

Book ID
116731228
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
95 KB
Volume
49
Category
Article
ISSN
0378-5122

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Sporadic cancers and familial breast cancers are characterized by an increase in genetic instability. Little is known about whether mismatch repair defects accompany this genetic instability. We investigated invasive and/or in situ breast cancers from 30 women with deleterious BRCA1/2 mutations and