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Oncogenic and Activated Wild-Typeras-p21 Proteins Induce Different Isoforms of Protein Kinase C in Mitogenic Signal Transduction

✍ Scribed by Lyndon Chie; Yongxia Qu; Denise Chung; Mohammed Boutjdir; Matthew R. Pincus


Book ID
114421921
Publisher
Springer
Year
2003
Tongue
English
Weight
65 KB
Volume
22
Category
Article
ISSN
1573-4943

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## Abstract The effects of P2Y2 purinoceptor activation on c‐Fos expression and the signaling pathways evoked by extracellular ATP/UTP in HeLa cells were investigated. We found that P2Y2 activation induced c‐Fos protein and phosphorylated the extracellular signal‐regulated kinases 1 and 2 (ERK1/2).