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Oncogenic anaplastic lymphoma kinase (ALK) mutation in neuroblastomas and other pediatric tumors

✍ Scribed by Mi Jung Kwon; Yoon-La Choi; Ki Woong Sung; So Young Kang; Sang Mo Park; Song-Yi Choi; Jung-Sun Kim; Yeon-Lim Suh


Book ID
116848052
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
405 KB
Volume
207
Category
Article
ISSN
0344-0338

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## Abstract The initial identification of the __ALK__ gene, expressed as C‐terminal part of the transforming fusion protein NPM‐ALK in the t(2;5)(p23;q35) lymphoma‐associated chromosomal translocation, revealed a novel receptor tyrosine kinase (RTK). In order to expand the knowledge on __ALK__ expr