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Oncogenes and Tumor Suppressor Genes in Breast Cancer: Potential Diagnostic and Therapeutic Applications

โœ Scribed by Osborne, C.


Book ID
117993982
Publisher
Alphamed Press
Year
2004
Tongue
English
Weight
259 KB
Volume
9
Category
Article
ISSN
1083-7159

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Tumor suppressor genes and breast cancer
โœ Thomas A. Buchholz; Michael M. Weil; Michael D. Story; Eric A. Strom; William A. ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 249 KB ๐Ÿ‘ 2 views

The genetic determinants for most breast cancer cases remain elusive. However, a mutation in a tumor suppressor gene, such as p53, BRCA1, BRCA2, or ATM, has been determined to be one mechanism of breast carcinogenesis. It has been established that inherited mutations in p53, BRCA1, and BRCA2 signifi