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Oncogene-induced up-regulation of Caco-2 cell proliferation involves IGF-II gene activation through a Protein kinase C-mediated pathway

โœ Scribed by Cadoret, A; Baron-Delage, S; Bertrand, F; Kornprost, M; Groyer, A; Gespach, C; Capeau, J; Cherqui, G


Book ID
110061498
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
584 KB
Volume
17
Category
Article
ISSN
0950-9232

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## Abstract The effects of P2Y2 purinoceptor activation on cโ€Fos expression and the signaling pathways evoked by extracellular ATP/UTP in HeLa cells were investigated. We found that P2Y2 activation induced cโ€Fos protein and phosphorylated the extracellular signalโ€regulated kinases 1 and 2 (ERK1/2).