Oncogene expression in a medullary thyroid carcinoma
✍ Scribed by Klimpfinger, Martin ;Ruhri, Christine ;Pütz, Barbara ;Pfragner, Roswitha ;Wirnsberger, Gerhard ;Höfler, Heinz
- Publisher
- Springer-Verlag
- Year
- 1987
- Weight
- 750 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0042-6431
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## Abstract ## Background. Recent studies have demonstrated that cyclooxygenase‐2 (COX‐2) expression is associated with the carcinogenesis of numerous neoplasms. The aim of this study was to evaluate the role of COX‐2 in medullary thyroid carcinoma (MTC). ## Methods. Tissue specimens of thyroid
Medullary thyroid carcinoma (MTC) is an uncommon tumour of calcitonin-secreting C-cells of the thyroid gland. This cancer represents an important potential model for the study of mechanisms of human epithelial cell transformation. Although recent studies have identified the gene involved in familial