Engraftment of chronic myeloid leukemia
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Christine F. Hoyle; Robert S. Negrin
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Article
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1998
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John Wiley and Sons
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English
β 290 KB
π 2 views
Chronic myeloid leukemia (CML) is a clonal disorder of primitive hematopoietic stem cells characterized by a reciprocal translocation between chromosomes 9 and 22. Animal models of CML would be useful to study the biology and potential therapies in this disease. Mice with severe combined immunodefic