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Oncogene-dependent engraftment of human myeloid leukemia cells in immunosuppressed mice

✍ Scribed by Kiser, M; McCubrey, J A; Steelman, L S; Shelton, J G; Ramage, J; Alexander, R L; Kucera, G L; Pettenati, M; Willingham, M C; Miller, M S


Book ID
110054855
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
352 KB
Volume
15
Category
Article
ISSN
0887-6924

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Engraftment of chronic myeloid leukemia
✍ Christine F. Hoyle; Robert S. Negrin πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 290 KB πŸ‘ 2 views

Chronic myeloid leukemia (CML) is a clonal disorder of primitive hematopoietic stem cells characterized by a reciprocal translocation between chromosomes 9 and 22. Animal models of CML would be useful to study the biology and potential therapies in this disease. Mice with severe combined immunodefic