## Abstract Cloned hybridoma cell lines were obtained by fusion of murine myeloma cells with spleen lymphocytes of either F344 rats or BALB/c mice immunized against the malignant F344 tracheal cell line, 2β10β1. Monoclonal antibodies were selected for their ability to bind to the immunizing cell li
Oncogene alterations in in vitro transformed rat tracheal epithelial cells
β Scribed by Marc J. Mass; Nancy S. Schorschinsky; Jessica A. Lasley; Diane K. Beeman; Stephen J. Austin
- Book ID
- 113255446
- Publisher
- Elsevier Science
- Year
- 1990
- Weight
- 914 KB
- Volume
- 243
- Category
- Article
- ISSN
- 0165-7992
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Five tumor-derived cell lines established from transformed rat tracheal epithelial (RTE) cells were examined for activated oncogenes using the NIH 3T3 assay, and the expression of 11 cellular oncogenes in the transformed cells was quantitated and compared with expression in normal RTE cells. DNA fro
## Abstract The purpose of our studies was to define abnormalities in the transforming growth factorβΞ² (TGFβΞ²) system of transformed rat tracheal epithelial (RTE) cells that might cause their abnormal growth behavior. We found that many, but not all, of the transformed cell lines were hyporesponsiv
The role of peptide growth factors in neoplastic progression of transformed rat tracheal epithelial (RTE) cells was assessed by examining growth factor requirements and expression o f growth factor and growth factor receptor genes in normal and transformed RTE cells. Neoplastically transformed cell