Oncogene addiction as a foundational rationale for targeted anti-cancer therapy: promises and perils

ErbB4 increases the proliferation potent

ErbB4 increases the proliferation potential of human lung cancer cells and its blockage can be used as a target for anti-cancer therapy

✍ Alex Starr; Joel Greif; Akiva Vexler; Maia Ashkenazy-Voghera; Valery Gladesh; Ch 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 218 KB 👁 1 views

## Abstract Clinical and experimental data suggest that ErbB‐4, a member of the epidermal growth factor receptor family, may have a role in cancer progression and response to treatment. We found recently, using a retrospective clinical analysis, that expression of ErbB‐4 receptor is correlated with